Singapore
Sixty-second Covid-19 breath test gets Singapore HSA’s provisional go-ahead, to be trialled at Tuas Checkpoint
60-second Covid-19 breath test gets HSAu00e2u20acu2122s provisional go-ahead, to be trialled at Tuas Checkpoint. u00e2u20acu201d National University of Singapore pic via TODAY

SINGAPORE, May 24 — A breath test that can detect a Covid-19 infection within a minute has received provisional authorisation from the Health Sciences Authority (HSA).

Developed by Breathonix — a spin-off from the National University of Singapore (NUS) — the BreFence Go Covid Breath Test System is the first breath analysis system to receive provisional authorisation here, NUS and Breathonix announced on Monday (May 24). 

Advertising
Advertising

Breathonix is working with the Ministry of Health to run a deployment trial at Tuas Checkpoint, which is set to start in a few days.

Incoming travellers will undergo the breath test, which will be done alongside a compulsory Covid-19 antigen rapid test, the university and Breathonix said in a statement.

Unlike standard Covid-19 tests that entail inserting a swab into a person’s nose or mouth, Breathonix’s breath test requires an individual only to blow into a disposable valve mouthpiece.

The exhaled breath is collected, measured and analysed for volatile organic compounds, which are produced by various biochemical reactions in human cells. 

The signature of these compounds varies between a healthy person’s breath and that of someone with an illness. Thus, changes in the compounds can be measured as markers for diseases such as Covid-19.

The exhaled breath is fed into an apparatus. A software algorithm then analyses the biomarkers and generates results in under a minute. 

Anyone who tests positive for coronavirus must undergo a confirmatory polymerase chain reaction swab test.

Dr Jia Zhunan, Breathonix’s chief executive, said: "Our breath test is non-invasive. Users only need to breathe out normally into the disposable mouthpiece provided, so there will not be any discomfort.

"Cross-contamination is unlikely as the disposable mouthpiece has a one-way valve and a saliva trap to prevent inhalation or saliva from entering the machine.”

NUS and Breathonix said that the breath test is easy to administer by trained staff members, but does not require medically trained professionals or laboratory processing.

The system underwent clinical trials from June last year to April this year.

The first two trials were at Singapore’s National Centre for Infectious Diseases and Changi Airport. A third trial was done in Dubai, United Arab Emirates, as part of a tie-up with the Dubai Health Authority and the Mohammed Bin Rashid University of Medicine and Health Sciences.

Three NUS graduates — Dr Jia, Du Fang and Wayne Wee Shi Jie — and Dr Jia’s doctoral adviser, Professor T Venky Venkatesan, founded Breathonix.

Strong commercial interest

NUS and Breathonix said that there was strong commercial interest in the system, and that the company was in talks with Singapore-based and overseas organisations.

Breathonix is supported by the NUS Graduate Research Innovation Programme, a scheme that supports deep-technology start-ups by its graduate students and research staff. Deep-tech start-ups are those relying on advanced scientific research.

Professor Freddy Boey, NUS’ deputy president for innovation and enterprise who leads the scheme, said: "Securing provisional authorisation in Singapore is a major milestone for Breathonix, and NUS is very proud of this achievement by our start-up.” — TODAY

Related Articles

 

You May Also Like